CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 447 enrolled
Drug / intervention
Brinzolamide/brimonidine ophthalmic suspension +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04944290
NCT04944290Phase 3Completed

Multi-Center, Randomized, Double-Masked, Active Controlled, Parallel Group Study to Compare Perrigo's Brinzolamide/Brimonidine Ophthalmic Suspension 1% to Simbrinza® in the Treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Both Eyes

Padagis LLC·interventional·Posted Jun 29, 2021·Updated Apr 2, 2025

In Brief

A Phase 3 clinical trial evaluating Brinzolamide/brimonidine ophthalmic suspension and Simbrinza 0.2%/1% Ophthalmic Suspension for Glaucoma, Open-Angle and Ocular Hypertension. Completed, enrolled 447 participants across 1 site.

Detailed Summary

To compare the efficacy and safety of Perrigo's product to an FDA approved product in the treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Both Eyes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
20222023202420252026
First PostedJun 29, 2021
Enrollment StartMay 28, 2021
Primary CompletionMar 11, 2022
Study CompletionJun 21, 2022
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 5.0 years ago

Interventions

Brinzolamide/brimonidine ophthalmic suspensiondrug

Test product

Simbrinza 0.2%/1% Ophthalmic Suspensiondrug

Reference product