CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 541 enrolled
Drug / intervention
Peer navigation +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04950153
NCT04950153N/ACompleted
CompareCT.gov

Intensive Combination Approach to Rollback the Epidemic in Nigerian Adolescents: UH3 Phase

Northwestern University·interventional·Posted Jul 6, 2021·Updated Apr 21, 2026

In Brief

A clinical study evaluating Peer navigation and SMS Text messaging for Adolescent HIV Infection. Completed, enrolled 541 participants across 6 sites.

Detailed Summary

Combination interventions with mHealth and Peer Navigation components will be evaluated in a randomized, stepped wedge trial among youth in Ibadan, Lagos, Sagamu, and Jos, Nigeria. Study findings will demonstrate whether or not the combination interventions for HIV treatment outcomes, which were found to be efficacious in our prior pilot UG3 trial, will remain efficacious if scaled as proposed in this UH3 trial, across multiple sites.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAdolescent HIV Infection
CountriesNigeria
CollaboratorsEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Timeline

N/ACompletedFinished
20222023202420252026
First PostedJul 6, 2021
Enrollment StartApr 15, 2021
Primary CompletionAug 30, 2024
Study CompletionDec 31, 2024
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 5.0 years ago

Interventions

Peer navigationbehavioral

Peer navigators will navigate youth with HIV to provide assistance and support to optimize adherence to antiretroviral treatment (ART)

SMS Text messagingbehavioral

Short Message System (SMS) text messages to remind and encourage youth to adhere to their ART