CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 15 enrolled
Drug / intervention
Psilocybin +1 moredrug
Likely dose
Psilocybin 25 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04950608
NCT04950608Phase 2Completed
CompareCT.gov

Pilot Study of Psilocybin-Assisted Therapy for Demoralization in Patients Receiving Hospice Care - PATH Study

Yvan Beaussant, MD, MSci·interventional·Posted Jul 6, 2021·Updated Feb 17, 2026

In Brief

A Phase 2 clinical trial evaluating Psilocybin and Psychotherapy for Hospice and 7 related conditions. Completed, enrolled 15 participants across 1 site.

Detailed Summary

The overall objective of this study is to develop and pilot test a novel regimen of psilocybin-assisted psychotherapy for demoralization in patients receiving hospice care. -The name of the study drug involved in this study is Psilocybin

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHospice, Psilocybin, Demoralization, Terminal Illness, Cancer-related Problem/Condition, Psychotherapy, Terminal Cancer, Cancer Terminal
CountriesUnited States
CollaboratorsOppenheimer Family Psychosocial Oncology and Palliative Care Research Grants, Usona Institute, Carey and Claudia Turnbull Family Foundation, Heffter Research Institute, George Sarlo Foundation, RiverStyx Foundation, Council on Spiritual Practices Fund at the San Francisco Foundation, Nikean Foundation, Jack Smith

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedJul 6, 2021
Enrollment StartMar 9, 2022
Primary CompletionJul 27, 2024
Study CompletionDec 31, 2025
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 5.0 years ago

Interventions

Psilocybindrug

Oral, single administration, dosage 25 mg orally

Psychotherapybehavioral

The treatment regimen consists of a single administration of psilocybin orally combined with a supportive psychotherapy including 2 preparation sessions and 2 integration sessions