CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 142 enrolled
Drug / intervention
remimazolam +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04950621
NCT04950621N/ACompleted

Comparison of Efficacy and Safety of Remimazolam and Propofol in Patients Undergoing Endovascular Procedures of Cerebrovascular Disorders: A Single-center,Randomized,Single-blind, Non-inferiority Trial

Air Force Military Medical University, China·interventional·Posted Jul 6, 2021·Updated Oct 20, 2022

In Brief

A clinical study evaluating remimazolam and propofol for Cerebrovascular Disorders and Anesthesia. Completed, enrolled 142 participants across 1 site.

Detailed Summary

Remimazolam, a novel ultra-short acting benzodiazepine that combined the advantages of midazolam and remifentanil, has been developed for procedural sedation, induction and maintenance of general anesthesia, and sedation in the ICU. Previous studies have suggested that efficacy and safety of remimazolam are not inferior to propofol or midazolam in patients undergoing colonoscopy,bronchoscopy and some other treatments. However, the efficacy and potential adverse effects of remimazolam on patients undergoing endovascular procedures of cerebrovascular disorders is still unclear. In this study, we tend to conduct a single-center, randomized, single-blind ,non-inferiority trial to compare the efficacy and safety of remimazolam and propofol in endovascular procedures of cerebrovascular disorders.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedJul 6, 2021
Enrollment StartJul 13, 2021
Primary CompletionJun 30, 2022
Study CompletionSep 30, 2022
TodayJul 2, 2026
Enrollment to primary: 12 monthsPosted 5.0 years ago

Interventions

remimazolamdrug

Remimazolam will be administered during induction and maintenance for general anesthesia.

propofoldrug

Propofol will be administered during induction and maintenance for general anesthesia.