CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 60 target
Drug / intervention
Physiotherapyother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04953637
NCT04953637N/AActiveUpdate OverdueUpdated 9mo ago · Completion was 7mo ago
Enrollment Stalled

Combined Physiotherapy and Deep Brain Stimulation to Improve Independent Community Mobility in Parkinson's Disease

University of Toronto·interventional·Posted Jul 8, 2021·Updated Sep 22, 2025

In Brief

A clinical study evaluating Physiotherapy for Parkinson Disease. Active but no longer recruiting, targeting 60 participants across 1 site.

Signals

Enrollment appears stalled

Detailed Summary

Deep brain stimulation (DBS) is the most commonly performed surgical treatment for individuals with Parkinson's disease (PD). DBS typically works best to lessen motor symptoms such as stiffness, slowness, and tremor. Despite an overall improvement of these motor symptoms with DBS, past research failed to show an increase in community mobility and have often reported an increase in falling after surgery. The ability to move around on one's own is important for functional independence and improved quality of life. There is growing evidence supporting the positive effects of physiotherapy on individuals with PD. Gait and balance training, in particular, can improve mobility and also prevent falls. So far, no study has shown the effectiveness of rehabilitation in patients receiving DBS. The purpose of this study is to determine if DBS combined with physiotherapy is effective for improving safe independent mobility in individuals with PD, more so than with patients receiving DBS alone.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada
Collaborators--

Timeline

N/AActiveOverdue
20222023202420252026
First PostedJul 8, 2021
Enrollment StartApr 15, 2021
Primary CompletionNov 30, 2025
Study CompletionDec 31, 2025
TodayJul 2, 2026
Enrollment to primary: 4.6 yearsPosted 5.0 years ago

Interventions

Physiotherapyother

Participants in the physiotherapy group will receive gait and balance focused physiotherapy at One Step Ahead Mobility physiotherapy clinic for 1-hour per day, 3 times/week for 8 weeks.