CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 19 enrolled
Drug / intervention
low carbohydrate diet +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04955691
NCT04955691N/ACompleted

Metabolic and Neurological Changes Induced by a Very Low Carbohydrate Diet in Youth With Type 1 Diabetes

Yale University·interventional·Posted Jul 9, 2021·Updated Oct 16, 2025

In Brief

A clinical study evaluating low carbohydrate diet and standard carbohydrate diet for Type1diabetes, Low Carbohydrate Diet. Completed, enrolled 19 participants across 1 site.

Detailed Summary

As more adolescents with type 1 diabetes (T1D) opt to follow very low carbohydrate diets to improve glucose control, it is becoming increasingly important to study the metabolic and neurological changes that occur on these diets and how these effect patient safety. Understanding the impact of dietary changes on metabolic and neurological factors will help guide clinical advice about the overall safety and efficacy of these diets in the pediatric T1D population. This work will be the basis of future studies testing dietary interventions to improve glycemic control and ensure that these dietary interventions are safe for growing youth with T1D.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20222023202420252026
First PostedJul 9, 2021
Enrollment StartJul 29, 2021
Primary CompletionAug 6, 2024
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 5.0 years ago

Interventions

low carbohydrate dietother

Participants will engage in a diet that limits carbohydrate intake to 15% of total daily calories for 2 weeks.

standard carbohydrate dietother

Participants will engage in a diet that recommends standard carbohydrate intake with respect to total daily calories for 2 weeks.