At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Procalcitonin to Reduce Antibiotic Use in Pediatric Pneumonia
In Brief
A Early Phase 1 clinical trial evaluating Amoxicillin and Placebo for Pneumonia and 3 related conditions. Completed, enrolled 5 participants across 3 sites.
Detailed Summary
This pilot study will evaluate study processes and feasibility of a future large-scale clinical trial that proposes to test whether low-risk children managed as outpatients with community-acquired pneumonia (CAP) and procalcitonin (PCT) levels \<0.25 ng/mL treated with placebo have a similar clinical response to those treated with antibiotics and fewer adverse effects.
Study Details
Timeline
Interventions
Participants will be randomized to receive oral amoxicillin for a standard course (10 days)
Participants will be randomized to receive oral placebo for a standard course (10 days)