CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 10 enrolled
Drug / intervention
Apraglutidedrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04964986
NCT04964986Phase 2Completed

A Multicenter, Open-label, Metabolic Balance Study to Evaluate the Effects of Apraglutide on Intestinal Absorption in Adult Subjects With Short Bowel Syndrome, Intestinal Failure (SBS-IF), and Colon-in-Continuity (CIC)

VectivBio AG·interventional·Posted Jul 16, 2021·Updated Jun 18, 2025

In Brief

A Phase 2 clinical trial evaluating Apraglutide for Short Bowel Syndrome. Completed, enrolled 10 participants across 2 sites in 2 countries.

Detailed Summary

The primary objective of the trial is to evaluate the safety of apraglutide in adult subjects with SBS-IF and CIC.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBelgium, France
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedJul 16, 2021
Enrollment StartJun 14, 2021
Primary CompletionJun 6, 2023
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 5.0 years ago

Interventions

Apraglutidedrug

Apraglutide is a synthetic peptide analogue of GLP-2 under development for treatment of SBS-IF, which acts as a full agonist at the GLP-2 receptor with in vitro potency and selectivity comparable with native GLP-2.