CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 504 enrolled
Drug / intervention
Nicotine Replacement Therapy +3 moredrug
Likely dose
Nicotine Replacement Therapy 21 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04965181
NCT04965181N/ACompleted

Mindfulness-based Smoking Cessation Enhanced With Mobile Technology

Georgia State University·interventional·Posted Jul 16, 2021·Updated Feb 27, 2026

In Brief

A clinical study evaluating Mindfulness-Based Addiction Treatment, Nicotine Replacement Therapy, and 2 other interventions for Cigarette Smoking. Completed, enrolled 504 participants across 1 site.

Detailed Summary

The purpose of this study is to: Aim I: Test the efficacy of a mindfulness-based text messaging program for smoking cessation ("iQuit Mindfully"), both as a standalone intervention and in combination with in-person counseling; and Aim II: Investigate the mechanisms through which mindfulness training impacts smoking cessation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20222023202420252026
First PostedJul 16, 2021
Enrollment StartJul 1, 2021
Primary CompletionJan 9, 2025
TodayJul 2, 2026
Enrollment to primary: 3.5 yearsPosted 5.0 years ago

Interventions

Mindfulness-Based Addiction Treatmentbehavioral

Mindfulness-based Addiction Treatment (MBAT) consists of 8 weekly virtual 2-hour sessions that teach mindfulness and cognitive-behavioral strategies for smoking cessation.

Nicotine Replacement Therapydrug

Patch therapy (beginning quit day) for participants who smoke \>10 cigarettes/day will consist of 4 weeks of 21 mg patches, 2 week of 14 mg patches, and 2 week of 7 mg patches. Patch therapy for participants who smoke less than 10 cigarettes/day will consist of 4 weeks of 14 mg patches and 4 weeks of 7 mg patches. Lozenge therapy (beginning quit day) for participants who smoke first cigarette within 30 minutes of waking up will consist of 8 weeks of 4mg lozenges. Lozenge therapy (beginning quit day) for participants who smoke first cigarette 30 minutes of more after they wake up will consist of 8 weeks of 2mg lozenges.

Self-help materialsbehavioral

Self-help materials for smoking cessation are based on the Treating Tobacco Use and Dependence Clinical Practice Guideline (Fiore et al., 2008) and include the "Clearing the Air" booklet developed by the National Cancer Institute (NCI) and a referral to the Tobacco Cessation Quitline (1-800-QUIT-NOW).

iQuit Mindfullybehavioral

iQuit Mindfully involves text messages on each day between treatment sessions. The text messages provide mindfulness and cognitive-behavioral strategies and support for smoking cessation.