CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 17 enrolled
Drug / intervention
BMS-986177 Oral Solution +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04965389
NCT04965389Phase 1Completed

A Study to Assess the Absolute Oral Bioavailability of Milvexian Using a 14C-Microtracer and Oral Solution in Healthy Participants With Additional Food Effect Comparison of a Spray-Dried Dispersion Formulation of Milvexian in Capsules

Bristol-Myers Squibb·interventional·Posted Jul 16, 2021·Updated Aug 21, 2023

In Brief

A Phase 1 clinical trial evaluating BMS-986177 Oral Solution, [14C]BMS-986177 Solution for Infusion, and 1 other intervention for Healthy Volunteers. Completed, enrolled 17 participants across 1 site.

Detailed Summary

The purpose of this study is to evaluate the absolute oral bioavailability (amount of drug entering the bloodstream) of spray-dried dispersion (SDD) milvexian capsules in the fed and fasted states, and to bridge the exposures seen using only the oral solution.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited Kingdom
Collaborators--

Timeline

Phase 1CompletedFinished
20222023202420252026
First PostedJul 16, 2021
Enrollment StartJul 16, 2021
Primary CompletionAug 22, 2021
Study CompletionOct 1, 2021
TodayJul 2, 2026
Enrollment to primary: 1 monthPosted 5.0 years ago

Interventions

BMS-986177 Oral Solutiondrug

Specified dose on specified days

[14C]BMS-986177 Solution for Infusiondrug

Specified dose on specified days

BMS-986177 Spray-dried Dispersion Capsulesdrug

Specified dose on specified days