At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Analgesic Efficacy of Single-shot Adductor Canal Block With Levobupivacaine and Dexmedetomidine in Total Knee Arthroplasty: a Randomized Clinical Trial
In Brief
A Phase 3 clinical trial evaluating Dexmedetomidine Hydrochloride and Levobupivacaine for Adductor Canal Block and 2 related conditions. Completed, enrolled 60 participants across 1 site.
Detailed Summary
Total knee arthroplasty surgery is associated with severe postoperative pain and adequate pain management is necessary for early postoperative mobilization and rehabilitation. Although good postoperative pain control may be achieved by continuous epidural anesthesia or femoral nerve block, both methods have adverse effects such as muscle weakness, which may delay postoperative mobilization.
Study Details
Timeline
Interventions
20 mL of 0.25% levobupivacaine plus 0.5 µg/kg dexmedetomidine
20 mL of 0.25% levobupivacaine plus 1 mL normal saline