CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 45 enrolled
Drug / intervention
Botulinum toxin type A +2 morebiological
Likely dose
Botulinum toxin type A 300 unitsfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04970407
NCT04970407Phase 1Completed

A Phase I, Randomised, Double-blind, Parallel-group, Single-centre Comparative Study to Evaluate the Pharmacodynamic Profile of Dysport®, Botox®, and Xeomin® in the Extensor Digitorum Brevis (EDB) Model in Healthy Adult Male Participants

Ipsen·interventional·Posted Jul 21, 2021·Updated Feb 19, 2025

In Brief

A Phase 1 clinical trial evaluating Botulinum toxin type A for Healthy Participants. Completed, enrolled 45 participants across 1 site.

Detailed Summary

Study aimed at comparing the pharmacodynamic profile (including duration of action) of three commercialized toxins by measuring the action potential of the injected muscle (extensor digitorum brevis)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited Kingdom
Collaborators--

Timeline

Phase 1CompletedFinished
20222023202420252026
First PostedJul 21, 2021
Enrollment StartJul 6, 2021
Primary CompletionMar 16, 2022
Study CompletionJun 8, 2022
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 4.9 years ago

Interventions

Botulinum toxin type Abiological

Intramuscular Injection, concentration 300 units (U)

Botulinum toxin type Abiological

Intramuscular Injection, concentration 50 U

Botulinum toxin type Abiological

Intramuscular Injection, concentration 50 U