CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 22 enrolled
Drug / intervention
Cold circulated water +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04973085
NCT04973085N/ACompleted

Effect of a Novel Cooling Device on Brain Temperature

University of Vermont·interventional·Posted Jul 22, 2021·Updated Sep 13, 2023

In Brief

A clinical study evaluating Cold circulated water and Body-temperature circulated water for Healthy. Completed, enrolled 22 participants across 1 site.

Detailed Summary

The objective of this study was to clarify whether neck cooling can be used to non-invasively lower brain temperature in healthy adults.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesUnited States

Timeline

N/ACompletedFinished
20222023202420252026
First PostedJul 22, 2021
Enrollment StartJul 22, 2021
Primary CompletionMar 3, 2022
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 4.9 years ago

Interventions

Cold circulated waterdevice

Cold water was circulated through an adhesive wrap applied to the front of the neck, overlying the carotid arteries, for 120 minutes. MR thermometry was used to measure core brain temperature in 1-minute intervals throughout the intervention. On a different day, subjects crossed over and repeated the intervention in the other study arm (i.e., cold went to body-temperature, and vice-versa).

Body-temperature circulated waterdevice

Body-temperature water was circulated through an adhesive wrap applied to the front of the neck, overlying the carotid arteries, for 120 minutes. MR thermometry was used to measure core brain temperature in 1-minute intervals throughout the intervention. On a different day, subjects crossed over and repeated the intervention in the other study arm (i.e., cold went to body-temperature, and vice-versa).