CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 2,843 enrolled
Drug / intervention
AZD1222 +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04973449
NCT04973449Phase 3Completed

A Phase II/III Partially Double-Blinded, Randomised, Multinational, Active-Controlled Study in Both Previously Vaccinated and Unvaccinated Adults to Determine the Safety and Immunogenicity of AZD2816, a Vaccine for the Prevention of COVID-19 Caused by Variant Strains of SARS-CoV-2

AstraZeneca·interventional·Posted Jul 22, 2021·Updated Sep 19, 2024

In Brief

A Phase 3 clinical trial evaluating AZD1222 and AZD2816 for COVID-19 and SARS-CoV-2. Completed, enrolled 2,843 participants across 35 sites in 4 countries.

Detailed Summary

The aim of the study is to assess the safety, and immunogenicity of AZD2816 for the prevention of coronavirus disease 2019 (COVID-19).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCOVID-19, SARS-CoV-2
CountriesBrazil, Poland, South Africa, United Kingdom
Collaborators--

Timeline

Phase 3CompletedFinished
20222023202420252026
First PostedJul 22, 2021
Enrollment StartJun 27, 2021
Primary CompletionFeb 4, 2022
Study CompletionAug 2, 2022
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 4.9 years ago

Interventions

AZD1222biological

10 mM histidine/histidine hydrochloride, 7.5% (w/v) sucrose, 35 mM sodium chloride, 1 mM magnesium chloride, 0.1% (w/v) polysorbate 80, 0.1 mM edetate disodium, 0.5% (w/v) ethanol, at pH 6.6.

AZD2816biological

10 mM histidine/histidine hydrochloride, 7.5% (w/v) sucrose, 35 mM sodium chloride, 1 mM magnesium chloride, 0.1% (w/v) polysorbate 80, 0.1 mM edetate disodium, 0.5% (w/v) ethanol, at pH 6.6.