At a glance
ClinicalIndex Comparison RecordN/ACompleted· 38 enrolled
Drug / intervention
Therapeutic plasma exchangeother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Therapeutic Plasma Exchange Followed by Convalescent Plasma Transfusion in Severe and Critically Ill COVID-19 Patients
In Brief
A clinical study evaluating Therapeutic plasma exchange for COVID-19 Pneumonia and 3 related conditions. Completed, enrolled 38 participants across 1 site.
Detailed Summary
Therapeutic plasma exchange (TPE) has been proposed as a rescue therapy in critically ill COVID-19 patients. The aim of this study is to determine whether combining TPE with convalescent plasma (CVP) transfusion early during the intensive care unit (ICU) stay, improves survival among this heterogeneous population.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCOVID-19 Pneumonia, COVID-19 Respiratory Infection, Acute Respiratory Failure, Acute Respiratory Distress Syndrome
CountriesRomania
Timeline
N/ACompletedFinished
202120222023202420252026
Enrollment StartJul 2020
Primary CompletionJan 2021
First PostedJul 2021
TodayJul 2026
First PostedJul 22, 2021
Enrollment StartJul 25, 2020
Primary CompletionJan 10, 2021
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 4.9 years ago
Interventions
Therapeutic plasma exchangeother
The intervention is a combination between the procedure of Therapeutic plasma exchange and biological transfusion of convalescent plasma from donors that have have COVID-19