CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 64 enrolled
Drug / intervention
INDV-2000 +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04976855
NCT04976855Phase 1Completed

A Phase I Double-Blind, Placebo-Controlled Randomized Study to Assess Repeated Doses of INDV-2000 (C4X_3256) up to 28 Days in Healthy Volunteers, and an Open-Label Study of INDV-2000 up to 11 Days in Treatment Seeking Individuals With Opioid Use Disorder

Indivior Inc.·interventional·Posted Jul 26, 2021·Updated Aug 21, 2024

In Brief

A Phase 1 clinical trial evaluating INDV-2000, Placebo, and 1 other intervention for Healthy Volunteer and Opioid-use Disorder. Completed, enrolled 64 participants across 3 sites.

Detailed Summary

The primary objectives for the study are: * Part I and Part II: Assess safety and tolerability of repeated doses of INDV-2000 in healthy volunteers. * Part III: Assess the safety and tolerability of repeated doses of INDV-2000 administered alone and with SUBOXONE sublingual (SL) film in an opioid use disorder (OUD) treatment seeking population.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 1CompletedFinished
20222023202420252026
First PostedJul 26, 2021
Enrollment StartAug 17, 2022
Primary CompletionJul 5, 2023
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 4.9 years ago

Interventions

INDV-2000drug

Capsule for oral administration

Placebodrug

Capsule for oral administration

SUBOXONE® sublingual filmdrug

Administered either under the tongue (sublingual) or between the gum and cheek (buccal)