CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,120 enrolled
Drug / intervention
Hydroxychloroquine +3 moredrug
Likely dose
Hydroxychloroquine 200 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04981379
NCT04981379Phase 3Completed

Efficacy and Safety of the Use of Hydroxychloroquine, Favipiravir or Hydroxychloroquine + Favipiravir in Early SARS-CoV-2 (COVID-19) Treatment

Health Institutes of Turkey·interventional·Posted Jul 29, 2021·Updated Jul 29, 2021

In Brief

A Phase 3 clinical trial evaluating Hydroxychloroquine, Favipiravir, and 2 other interventions for Covid19. Completed, enrolled 1,120 participants across 6 sites.

Detailed Summary

This study is a randomized, double-blinded, and placebo controlled phase III clinical trial which aims to investigate the superiority of hydroxychloroquine, favipiravir or hydroxychloroquine + favipiravir treatment, initiated especially in the early period in the treatment of COVID-19, over the patients being followed up with placebo in adults aged 18\~59 Years.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCovid19
CountriesTurkey (Türkiye)
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedJul 29, 2021
Enrollment StartNov 16, 2020
Primary CompletionJan 31, 2021
Study CompletionFeb 16, 2021
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 4.9 years ago

Interventions

Hydroxychloroquinedrug

Hydroxychloroquine (200 mg), as two tablets per day for 5-day interval + Placebo \[Favipiravir (1600 mg)\], as two tablet per day at the first day and then Favipiravir (600 mg) as two tablet per day for the remaining 4-day interval.

Favipiravirdrug

Favipiravir (1600 mg), as two tablet per day at the first day and then Favipiravir (600 mg) as two tablet per day for the remaining 4-day interval + Placebo \[Hydroxychloroquine (200 mg)\], as two tablets per day for 5-day interval.

Favipiravir + Hydroxychloroquinedrug

Favipiravir (1600 mg), as two tablet per day at the first day and then Favipiravir (600 mg) as two tablet per day for the remaining 4-day interval + Hydroxychloroquine (200 mg), as two tablets per day for 5-day interval.

Placebodrug

Placebo \[Favipiravir (1600 mg)\], as two tablet per day at the first day and then Placebo Favipiravir (600 mg) as two tablet per day for the remaining 4-day interval + Hydroxychloroquine (200 mg), as two tablets per day for 5-day interval.