CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 16 enrolled
Drug / intervention
[¹⁴C]-LY3484356 +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04991766
NCT04991766Phase 1Completed

An Open-label, Two-part Study of the Disposition and Absolute Bioavailability of [¹⁴C]-LY3484356 in Healthy Females of Non-Childbearing Potential

Eli Lilly and Company·interventional·Posted Aug 5, 2021·Updated Dec 5, 2025

In Brief

A Phase 1 clinical trial evaluating [¹⁴C]-LY3484356, LY3484356, and 1 other intervention for Healthy. Completed, enrolled 16 participants across 1 site.

Detailed Summary

The main purpose of this study is to measure how much of the study drug gets into the bloodstream and how long it takes the body to get rid of it. This study has two parts. It will involve a single dose of 14C radiolabeled LY3484356. This means that a radioactive substance C14 will be incorporated into the study drug, to investigate the study drug and its breakdown products, to find out how much of these pass from blood into urine, feces and expired air. The study will last about 4 weeks. Screening is required within 28 days prior to the start of the study and follow up is required approximately 7 days after discharge.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
20222023202420252026
First PostedAug 5, 2021
Enrollment StartAug 13, 2021
Primary CompletionApr 2, 2022
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 4.9 years ago

Interventions

[¹⁴C]-LY3484356drug

Administered orally.

LY3484356drug

Administered orally.

[¹⁴C]-LY3484356 (IV)drug

Administered IV.