CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 70 enrolled
Drug / intervention
Intravenous Administration of Lidocaine Post Cardiac Surgery +1 moredrug
Likely dose
Intravenous Administration of Lidocaine Post Cardiac Surgery 2 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04995497
NCT04995497Phase 2Completed

IV vs. Erector Spinae Plane Blocks-Cardiac Surgery

Archit Sharma·interventional·Posted Aug 9, 2021·Updated Apr 9, 2025

In Brief

A Phase 2 clinical trial evaluating Intravenous Administration of Lidocaine Post Cardiac Surgery and Administration of Lidocaine Post Cardiac Surgery via ESP Catheter for Erector Spinae Plane Block and 2 related conditions. Completed, enrolled 70 participants across 1 site.

Detailed Summary

Interfascial plane blocks have been developed for analgesia, among which the erector spinae plane (ESP) has gained popularity. The ESP block has been hypothesized to provide truncal analgesia by spread of local anesthetic into the paravertebral space. Recent studies have contested this idea showing unreliability in the spread of the local anesthetic into the paravertebral space.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedAug 9, 2021
Enrollment StartAug 15, 2021
Primary CompletionApr 7, 2023
Study CompletionApr 30, 2023
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 4.9 years ago

Interventions

Intravenous Administration of Lidocaine Post Cardiac Surgerydrug

Lidocaine will be administered via intravenously. Initial dose will be at 2 mg/kg ideal body weight followed by dosing at 2 mg/kg/hr for 48 hours

Administration of Lidocaine Post Cardiac Surgery via ESP Catheterdrug

Lidocaine will be administered via ESP catheter. Initial dose will be at 2 mg/kg ideal body weight split between two catheters followed by dosing at 2 mg/kg/hr for 48 hours