CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 25 enrolled
Drug / intervention
Crest Whitening Emulsionsdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04996069
NCT04996069N/ACompleted

Exploratory Study on Effect of Whitening Agent With Emulsion Gel in Xerostomic Population

Tufts University·interventional·Posted Aug 9, 2021·Updated Jul 26, 2024

In Brief

A clinical study evaluating Crest Whitening Emulsions for Xerostomia. Completed, enrolled 25 participants across 1 site.

Detailed Summary

Xerostomia, is a subjective sensation of dryness of the mouth. There are more than 700 medications that can lead to the salivary hypofunction that results in dry mouth. This study will investigate a semi solid cohesive gel (referred to as Whitening Gel) that has the primary marketed purpose of teeth whitening. We theorize that the whitening gel's retention in the oral cavity is longer than rinse forms and this is likely to promote the flow of saliva by stimulating taste buds which could alleviate the sensation of dryness in the oral cavity. This will be a single center, two visit study investigating the effectiveness of dryness in the oral cavity, whiteness of teeth, and teeth sensitivity after one week's use of whitening agent.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsXerostomia
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedAug 9, 2021
Enrollment StartAug 9, 2021
Primary CompletionApr 26, 2022
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 4.9 years ago

Interventions

Crest Whitening Emulsionsdevice

Subjects with Xerostomia will be asked to apply the study intervention product to their teeth up to 4 times per day for 1 week to investigate if the study intervention product increases saliva production in this dry mouth populaiton.