CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 200 enrolled
Drug / intervention
MLS-101 (Part I) +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05001945
NCT05001945Phase 2Completed

A Randomized, Double-blind, Placebo-controlled, Dose-ranging, Multicenter Phase 2 Study to Evaluate the Safety, Efficacy, and Tolerability of MLS-101 in Subjects With Uncontrolled Hypertension

Mineralys Therapeutics Inc.·interventional·Posted Aug 12, 2021·Updated Jan 5, 2024

In Brief

A Phase 2 clinical trial evaluating MLS-101 (Part I), Placebo (Part I), and 2 other interventions for Hypertension, Renal. Completed, enrolled 200 participants across 44 sites.

Detailed Summary

A randomized, double-blind, placebo-controlled, dose-ranging, Phase II study to evaluate the safety, efficacy, and tolerability of MLS-101 in Subjects With Uncontrolled Hypertension

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedAug 12, 2021
Enrollment StartJul 1, 2021
Primary CompletionSep 7, 2022
Study CompletionOct 7, 2022
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 4.9 years ago

Interventions

MLS-101 (Part I)drug

MLS-101 tablet(s) by mouth once or twice daily.

Placebo (Part I)other

Placebo tablet(s) by mouth once or twice daily.

Placebo (Part II)other

Placebo tablet(s) by mouth once daily.

MLS-101 (Part II)drug

MLS-101 tablet(s) by mouth once daily.