CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 64 enrolled
Drug / intervention
Aerobic Training +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05002218
NCT05002218N/ACompleted

The Neural Effects of Balance Versus Aerobic Training in Individuals With Degenerative Cerebellar Diseases

Columbia University·interventional·Posted Aug 12, 2021·Updated Nov 4, 2025

In Brief

A clinical study evaluating Aerobic Training and Balance Training for Cerebellar Ataxia. Completed, enrolled 64 participants across 1 site.

Detailed Summary

Balance and aerobic training show promise as treatments for degenerative cerebellar diseases, but the neural effects of both training methods are unknown. The goal of this project is to evaluate how each training method impacts the brain, and particularly, the degenerating cerebellum. Various neuroimaging techniques will be used to accomplish this goal and test the hypothesis that balance training impacts brain structures outside the cerebellum whereas aerobic training causes more neuroplastic changes within the cerebellum.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20222023202420252026
First PostedAug 12, 2021
Enrollment StartJan 31, 2022
Primary CompletionNov 6, 2024
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 4.9 years ago

Interventions

Aerobic Trainingbehavioral

Aerobic training on stationary bike 5x a week for 30 minutes a day.

Balance Trainingbehavioral

Balance training 5x a week for 30 minutes as instructed by a therapist. Standard of care.