CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 451 enrolled
Drug / intervention
Dotinurad +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05007392
NCT05007392Phase 3Completed

A Randomized, Multicenter, Double-Blind, Superiority Study of Dotinurad (4 mg) and Febuxostat (40 mg) for the Treatment of Subjects With Gout

Eisai Co., Ltd.·interventional·Posted Aug 16, 2021·Updated Jul 30, 2025

In Brief

A Phase 3 clinical trial evaluating Dotinurad, Febuxostat, and 2 other interventions for Gout. Completed, enrolled 451 participants across 30 sites.

Detailed Summary

The primary purpose of the study is to confirm the efficacy of dotinurad 4 milligram (mg) to febuxostat 40 mg on the percentage of participants achieving a serum uric acid (SUA) level less than or equal to (\<=) 6.0 milligrams per deciliter (mg/dL) at Week 24 in Chinese participants with gout.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGout
CountriesChina
Collaborators--

Timeline

Phase 3CompletedFinished
20222023202420252026
First PostedAug 16, 2021
Enrollment StartDec 21, 2021
Primary CompletionJun 14, 2023
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 4.9 years ago

Interventions

Dotinuraddrug

Dotinurad oral tablets.

Febuxostatdrug

Febuxostat oral tablets.

Dotinurad Matched Placeboother

Dotinurad matched placebo oral tablets.

Febuxostat Matched Placeboother

Febuxostat matched placebo oral tablets.