CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 124 enrolled
Drug / intervention
Information-Motivation-Behavioral skills (IMB) model-based intervention +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

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Search/NCT05008211
NCT05008211N/ACompleted

Effectiveness of an Information-Motivation-Behavioral Skills Model-based Intervention on Adherence to Domiciliary Non-invasive Ventilation of Patients With Chronic Hypercapnic Respiratory Failure: A Randomized Controlled Study

The University of Hong Kong·interventional·Posted Aug 17, 2021·Updated Nov 28, 2025

In Brief

A clinical study evaluating Information-Motivation-Behavioral skills (IMB) model-based intervention and Control - usual care for Hypercapnic Respiratory Failure and Noninvasive Ventilation. Completed, enrolled 124 participants across 1 site.

Detailed Summary

Domiciliary non-invasive ventilation (NIV) is a standard care for improving survival rates of selected patients with chronic hypercapnic respiratory failure (CHRF) and to improve the patients' hypercapnia, sleep quality, health-related quality of life (QoL). Adherence is an important factor affecting clinical effectiveness of domiciliary NIV. Our previous study has noted the associations between poor domiciliary NIV adherence and increased number of clinical adverse events (p = 0.004) and increased hospitalization requiring acute NIV salvage (p = 0.042). However, there are very limited studies on adherence to domiciliary NIV in patients with CHRF. The only interventional study was a single-group pre-test post-test study and lack of a theoretical framework for guiding the intervention. This study is employing an Information-Motivation-Behavioral skills (IMB) model-based intervention to improve inhalation adherence in a group of chronic obstructive pulmonary disease (COPD) patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesHong Kong

Timeline

N/ACompletedFinished
20222023202420252026
First PostedAug 17, 2021
Enrollment StartSep 16, 2021
Primary CompletionOct 16, 2024
Study CompletionJun 30, 2025
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 4.9 years ago

Interventions

Information-Motivation-Behavioral skills (IMB) model-based interventionother

A six-week programme

Control - usual careother

he nurse will provide an one-hour face-to-face session to introduce the choices of domiciliary NIV and teach the patient or his/her family on how to operate and maintain the ventilator, interface and accessories, and also how to handle the common problems