CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 28 enrolled
Drug / intervention
Exib 120 mg etoricoxib film-coated tablets +1 moredrug
Likely dose
Exib 120 mg etoricoxib film-coated tabletsfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05014490
NCT05014490Phase 1Completed

Randomized, Open-label, Single-dose, Two-sequence, Two-period, Crossover, Comparative, Oral Bioequivalence Study of Exib 120 mg Etoricoxib Film-coated Tablets (PrJSC "Pharmaceutical Firm "Darnitsa") and Arcoxia 120 mg Etoricoxib Film-coated Tablets (Merck Sharp&Dohme B.V.) in Healthy, Adult Volunteers Under Fasting Conditions

Darnitsa Pharmaceutical Company·interventional·Posted Aug 20, 2021·Updated Nov 29, 2024

In Brief

A Phase 1 clinical trial evaluating Exib 120 mg etoricoxib film-coated tablets and Arcoxia® 120 mg etoricoxib film-coated tablets for Bioequivalence and Healthy Subjects. Completed, enrolled 28 participants across 1 site.

Detailed Summary

The present study is a comparative bioavailability study performed to assess bioequivalence between a Test medication (Exib 120 mg etoricoxib film-coated tablets manufactured by PrJSC "Pharmaceutical firm "Darnitsa" \[Ukraine\]) and a Reference medication (marketed medicinal product Arcoxia® 120 mg etoricoxib film-coated tablets, Marketing Authorisation Holder: UAB "Merck Sharp\&Dohme", Lithuania) in healthy volunteers.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesTurkey (Türkiye)
CollaboratorsAnapharm

Timeline

Phase 1CompletedFinished
202120222023202420252026
First PostedAug 20, 2021
Enrollment StartFeb 24, 2021
Primary CompletionMar 24, 2021
TodayJul 2, 2026
Enrollment to primary: 1 monthPosted 4.9 years ago

Interventions

Exib 120 mg etoricoxib film-coated tabletsdrug

Oral, COX-2 highly selective, non-steroidal anti-inflammatory generic drug

Arcoxia® 120 mg etoricoxib film-coated tabletsdrug

Oral, COX-2 highly selective, non-steroidal anti-inflammatory innovative drug