CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 160 enrolled
Drug / intervention
PTeye +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05022641
NCT05022641N/ACompleted

Evaluating Impact of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy

University of Michigan·interventional·Posted Aug 26, 2021·Updated Aug 27, 2025

In Brief

A clinical study evaluating PTeye and Standard of Care for Parathyroid Adenoma and 4 related conditions. Completed, enrolled 160 participants across 1 site.

Detailed Summary

This study will see if the use of near infrared autofluorescence (NIRAF) detection with an FDA-cleared device 'Parathyroid Eye (PTeye)' for identifying parathyroid glands (PGs) during parathyroidectomy (PTx) procedures is better than a surgeon's detection alone. It compares risk-benefits and outcomes in PTx patients where NIRAF detection with PTeye for parathyroid identification is either used or not used. Parathyroidectomy - look at application of the technology to see if it assists during a parathyroidectomy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20222023202420252026
First PostedAug 26, 2021
Enrollment StartDec 1, 2021
Primary CompletionMay 31, 2024
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 4.9 years ago

Interventions

PTeyedevice

The surgeon will first take 5 baseline NIRAF measurements on the thyroid gland (or neck muscle, if thyroid is absent) using the disposable sterile fiber probe that is connected to the PTeye console (see Figure 1), as per device functionality requirements.

Standard of Careother

The surgeon will rely solely on her/his surgical experience in identifying the parathyroid glands during the operations.