CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 616 enrolled
Drug / intervention
Hyfe Cough Tracker +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05042063
NCT05042063N/ACompleted

Acoustic Cough Monitoring for the Management of Patients With Known Respiratory Disease

Clinica Universidad de Navarra, Universidad de Navarra·observational·Posted Sep 13, 2021·Updated Nov 20, 2025

In Brief

An observational study evaluating Hyfe Cough Tracker and Hyfe Air for Cough and 6 related conditions. Completed, enrolled 616 participants across 1 site.

Detailed Summary

This study pretends to evaluate the potential use of Hyfe Cough Tracker (Hyfe) to screen for, diagnose, and support the clinical management of patients with respiratory diseases, while enriching a dataset of disease-specific annotated coughs, for further refinement of similar systems.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesSpain

Timeline

N/ACompletedFinished
20222023202420252026
First PostedSep 13, 2021
Enrollment StartSep 15, 2021
Primary CompletionSep 15, 2022
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 4.8 years ago

Interventions

Hyfe Cough Trackerdevice

Hyfe Cough Tracker is a digital acoustic surveillance system that uses an artificial intelligence system to discriminate cough from non-cough sounds. Hyfe is an AI-enabled mobile app that records short snippets (\<0.5 seconds) of putative cough explosive sounds and then classifies them as cough or non-cough using a convolutional neural network (CNN) model. Briefly, the acoustic characteristics of recorded sounds are converted into an image file, which is then processed by an algorithm trained to identify graphical differences in images. This creates an adjustable prediction score, with values above it, resulting in a sound being classified as "cough", and those below being classified as "non-cough.

Hyfe Airdevice

Hyfe Air is a wearable device with an incorporated wireless lapel microphone. The device´s recordings can be run through the same cough-detection algorithm used by Hyfe Cough Tracker, while its results are directly stored in a remote database and are not displayed to participants.