CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 26 enrolled
Drug / intervention
Very low calorie dietdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05055154
NCT05055154N/ACompleted
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Oxidative Stress and L-CBMN Cytome Assay Parameters Levels in Severely Obese With BMI ≥ 35kg/m2 After 3 Weeks 567 kcal Hospital Controlled VLCD

Special Hospital for Extended Treatment of Duga Resa·interventional·Posted Sep 24, 2021·Updated Sep 24, 2021

In Brief

A clinical study evaluating Very low calorie diet for Obesity and 2 related conditions. Completed, enrolled 26 participants across 1 site.

Detailed Summary

Obesity leads to physiological imbalance resulting in hyperglycemia, dyslipidaemia and inflammation and can generate systematic oxidative stress through multiple biochemical mechanisms. Oxidative stress (OS) can induce DNA damage and inhibit DNA repair mechanisms. Very low calorie diet (VLCD) have rapid positive effect on weight loss, glucose homeostasis, insulin resistance, inflammation and OS. The aim of this study is to determine the effect of a three-week VLCD on anthropometric, biochemical and genomic parameters in individuals with BMI ≥ 35kg/m2.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsObesity, Weight Loss, DNA Damage
CountriesCroatia
CollaboratorsInstitute for Medical Research and Occupational Health, University of Zagreb

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedSep 24, 2021
Enrollment StartJun 14, 2019
Primary CompletionNov 3, 2020
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 4.8 years ago

Interventions

Very low calorie dietdevice

In hospital patients will eat prepared diet with 567 kcal a day during 3 weeks