CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 368 enrolled
Drug / intervention
Digital Diabetes Prevention Program (dDPP) +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05056376
NCT05056376N/ACompleted

Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Programs

Johns Hopkins University·interventional·Posted Sep 24, 2021·Updated Dec 17, 2025

In Brief

A clinical study evaluating Digital Diabetes Prevention Program (dDPP) and Human Coach-based Diabetes Prevention Program (hDPP) for PreDiabetes and 10 related conditions. Completed, enrolled 368 participants across 2 sites.

Detailed Summary

The purpose of this research study is to compare the effectiveness of a fully automated digital diabetes prevention program to standard of care human coach-based diabetes prevention programs for promoting clinically meaningful lifestyle changes to reduce the risk of type 2 diabetes in adults with prediabetes.

Study Details

Timeline

N/ACompletedFinished
20222023202420252026
First PostedSep 24, 2021
Enrollment StartOct 1, 2021
Primary CompletionDec 16, 2024
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 4.8 years ago

Interventions

Digital Diabetes Prevention Program (dDPP)behavioral

The Sweetch app is a hyper-personalized mobile digital coach that provides users with tailored recommendations to promote healthy lifestyle behaviors (150 minutes per week of physical activity, weight reduction, and healthy eating habits) to reduce the risk of type 2 diabetes. The Sweetch app uses self-tracking and multiple evidence-based persuasive eCoaching strategies. The Sweetch artificial intelligence algorithm delivers just-in-time support and/or adapt recommendations based on the user's response. For example, push notifications will be sent when the algorithm detects that the user is potentially available and able to act upon the recommendation, based on various parameters including location, previous response, calendar availability, and weather, etc.

Human Coach-based Diabetes Prevention Program (hDPP)behavioral

The Human Coach-Based Diabetes Prevention Program will consist of a CDC recognized lifestyle change program. Participants will attend a total of 16 weekly sessions during months 1 to 6 and 6 sessions during months 7 to 12. These group sessions may be delivered in-person at the local program or remotely using video conferencing. During these sessions, participants will receive information about lifestyle change behaviors focusing on weight loss, physical activity, and nutrition from a trained lifestyle coach.