CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 770 enrolled
Drug / intervention
RSVPreF3 OA investigational vaccinebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05059301
NCT05059301Phase 3Completed

A Phase 3, Randomized, Double-blind, Multi-country Study to Evaluate Consistency, Safety, and Reactogenicity of 3 Lots of RSVPreF3 OA Investigational Vaccine Administrated as a Single Dose in Adults Aged 60 Years and Above

GlaxoSmithKline·interventional·Posted Sep 28, 2021·Updated Feb 15, 2023

In Brief

A Phase 3 clinical trial evaluating RSVPreF3 OA investigational vaccine for Respiratory Syncytial Virus Infections. Completed, enrolled 770 participants across 19 sites in 3 countries.

Detailed Summary

The purpose of this study is to assess the lot-to-lot consistency in terms of immunogenicity and evaluate the safety and reactogenicity of 3 lots of the RSVPreF3 OA investigational vaccine administered as a single dose in adults ≥ 60 years of age (YOA).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, Sweden, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20222023202420252026
First PostedSep 28, 2021
Enrollment StartOct 1, 2021
Primary CompletionJan 24, 2022
Study CompletionJun 30, 2022
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 4.8 years ago

Interventions

RSVPreF3 OA investigational vaccinebiological

One dose of a unique combination of the RSVPreF3 antigen lots (Lot 1, Lot 2 or Lot 3) and extemporaneously reconstituted with AS01E adjuvant lots (Lot A, Lot B and Lot C), administered intramuscularly in the deltoid region of the non-dominant arm, at Day 1.