CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 24 enrolled
Drug / intervention
TAK-881biological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05059977
NCT05059977Phase 1Completed

A Phase 1, Single-Dose, Single-Center, Open-Label, Three-Arm Study to Assess the Tolerability and Safety of Immune Globulin Subcutaneous (Human), 20% Solution With Recombinant Human Hyaluronidase (TAK-881) at Various Infusion Rates in Healthy Adult Subject

Takeda·interventional·Posted Sep 28, 2021·Updated Jan 12, 2024

In Brief

A Phase 1 clinical trial evaluating TAK-881 for Healthy Volunteers. Completed, enrolled 24 participants across 1 site.

Detailed Summary

The main aims of this study are to check for side effects from TAK-881 in healthy adults and to learn how much TAK-881 they can receive without getting side effects from it. During the study, participants will receive one infusion of TAK-881 under the skin (subcutaneous infusion) on Day 1 at a lower dose level followed by participants receiving one infusion of higher dose levels with ongoing safety monitored by the doctor to ensure optimal tolerability and safety. Participants will stay in the clinic for 4 days and will come back after 4 weeks. A follow up visit will take place 12 weeks after the TAK-881 infusion.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 1CompletedFinished
20222023202420252026
First PostedSep 28, 2021
Enrollment StartOct 12, 2021
Primary CompletionApr 12, 2022
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 4.8 years ago

Interventions

TAK-881biological

Participants will receive subcutaneous infusion of TAK-881 on Day 1.