CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 35 enrolled
Drug / intervention
Itacitinibdrug
Likely dose
Itacitinib 300 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05063110
NCT05063110Phase 2Completed

Treatment of Non Severe Hemophagocytosis Lymphohistiocytosis With ITACITINIB a Phase II Prospective Trial

Assistance Publique - Hôpitaux de Paris·interventional·Posted Sep 30, 2021·Updated Dec 26, 2025

In Brief

A Phase 2 clinical trial evaluating Itacitinib for Adults Patients Having Non Severe HLH. Completed, enrolled 35 participants across 1 site.

Detailed Summary

This project aims to test the effectiveness of ITACITINIB in sporadic Hemophagocytosis Lymphohistiocytosis (HLHs)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesFrance
CollaboratorsIncyte Corporation

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedSep 30, 2021
Enrollment StartMay 3, 2022
Primary CompletionApr 3, 2025
Study CompletionOct 1, 2025
TodayJul 2, 2026
Enrollment to primary: 2.9 yearsPosted 4.8 years ago

Interventions

Itacitinibdrug

Administration of 300 mg of ITACITINIB per os every day for 30 days.