CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 54 enrolled
Drug / intervention
Felzartamab +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05065970
NCT05065970Phase 2Completed

A Double Blind, Randomized, Placebo-Controlled, Multicenter Phase IIa, Clinical Trial to Assess Efficacy and Safety of the Human Anti-CD38 Antibody Felzartamab in IgA Nephropathy

HI-Bio, A Biogen Company·interventional·Posted Oct 4, 2021·Updated Apr 28, 2026

In Brief

A Phase 2 clinical trial evaluating Felzartamab and Placebo for Immunoglobulin A (IgA) Nephropathy. Completed, enrolled 54 participants across 59 sites in 15 countries.

Detailed Summary

Randomized, placebo-controlled, multi-center, double-blind, proof of concept phase IIa trial and dose evaluation trial of felzartamab in IgAN

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Belgium, Bulgaria, Czechia, Georgia, Germany, Japan, Malaysia, Philippines, Serbia, South Korea, Spain, Taiwan, Ukraine, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedOct 4, 2021
Enrollment StartAug 31, 2021
Primary CompletionFeb 6, 2023
Study CompletionMay 6, 2024
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 4.7 years ago

Interventions

Felzartamabdrug

anti-CD38+ monoclonal antibody

Placeboother

Placebo comparator