CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 37 enrolled
Drug / intervention
Pulmonary resectionprocedure
Likely dose
Not stated in record
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Search/NCT05067881
NCT05067881N/ACompleted

Post COVID-19 Pneumo-hematocele: Clinical Presentation and Treatment Pathway

Hospital General Ajusco Medio·observational·Posted Oct 5, 2021·Updated Oct 5, 2021

In Brief

An observational study evaluating Pulmonary resection for COVID-19 Respiratory Infection. Completed, enrolled 37 participants across 1 site.

Detailed Summary

Introduction. As the COVID-19 pandemic has continued, an increasing number of long-term complications are emerging. Recently, the appearance of characteristic pulmonary lesions has been noted, being described as post COVID-19 pneumatocele. The aim of this study is to describe the clinical, histopathologic and imaging features of post COVID-19 pneumo-hematoceles (PHC) and secondarily to suggest a treatment algorithm in these patients. Methods. A retrospective study was performed in patients admitted with diagnosis of SARS-CoV2 infection from March 2020 to September 2021 who presented PHC on imaging studies. Clinical and demographic variables were recorded and CT scans were analyzed. A logistic regression analysis was performed to determine the risk for rupture according to PHC characteristics. It appears that PHC occurs secondary to encapsulation of blood accumulation, the result of micro capillary bleeding, with partial reabsorption of blood and subsequent air filling. The recommendation is to operate on patients with PHC of 5cm and those with persistent lesions of 3cm.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesMexico

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedOct 5, 2021
Enrollment StartMar 1, 2020
Primary CompletionMar 1, 2020
Study CompletionSep 20, 2021
TodayJul 2, 2026
Enrollment to primary: 0 daysPosted 4.7 years ago

Interventions

Pulmonary resectionprocedure

Resection of pneumohematocele