CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 438 enrolled
Drug / intervention
Intravenous glenzocimab (ACT017) 1000 mg +1 moredrug
Likely dose
Intravenous glenzocimab (ACT017) 1000 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05070260
NCT05070260Phase 3Completed

A Randomized, Double Blind, Multicenter, Multinational, Placebo Controlled, Parallel Group, Single Dose, Adaptive Efficacy and Safety Study of Glenzocimab Used as an add-on Therapy on Top of Standard of Care un the 4.5 Hours Following an Acute Ischemic Stroke

Acticor Biotech·interventional·Posted Oct 7, 2021·Updated Jul 3, 2024

In Brief

A Phase 3 clinical trial evaluating Intravenous glenzocimab (ACT017) 1000 mg and Intravenous Placebo for Acute Ischemic Stroke. Completed, enrolled 438 participants across 10 sites in 2 countries.

Detailed Summary

A randomized, double blind, multicenter, multinational, placebo controlled, parallel group, single dose, adaptive phase II/III study. The study evaluates the efficacy and safety of a fixed dose of glenzocimab (1000 mg IV over 6 hrs including initial bolus of 15 minutes) on top of the best standard of care.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesGermany, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20222023202420252026
First PostedOct 7, 2021
Enrollment StartSep 23, 2021
Primary CompletionApr 30, 2024
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 4.7 years ago

Interventions

Intravenous glenzocimab (ACT017) 1000 mgdrug

Add-on therapy to the standard of Care in the treatment of the acute ischemic stroke symptoms

Intravenous Placebodrug

Add-on therapy to the standard of Care in the treatment of the acute ischemic stroke symptoms