CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 21 enrolled
Drug / intervention
Amivantamabdrug
Likely dose
Amivantamab 1050mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05074940
NCT05074940Phase 2Active

Phase II Study to Evaluate Amivantamab in Recurrent and Metastatic Adenoid Cystic Carcinoma

Trisha Wise-Draper·interventional·Posted Oct 12, 2021·Updated May 8, 2026

In Brief

A Phase 2 clinical trial evaluating Amivantamab for Salivary Gland Cancer. Active but no longer recruiting, targeting 21 participants across 5 sites.

Detailed Summary

The purpose of the study is to determine if treatment with amivantamab will be efficacious in patients with recurrent and metastatic adenoid cystic carcinoma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2Active
2022202320242025202620272028
First PostedOct 12, 2021
Enrollment StartAug 5, 2022
Primary CompletionMar 2, 2026
Study CompletionAug 5, 2028
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 4.7 years ago

Interventions

Amivantamabdrug

Patients will receive amivantamab at 1050mg weekly for the first cycle and biweekly thereafter (1400mg for patients ≥80kg).