CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 15 enrolled
Drug / intervention
BI 425809 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05076409
NCT05076409Phase 1Completed

Effect of Fluconazole on the Pharmacokinetics of a Single Oral Dose of BI 425809 in Healthy Male Subjects (an Open-label, Two-period Fixed-sequence Design Study)

Boehringer Ingelheim·interventional·Posted Oct 13, 2021·Updated May 4, 2026

In Brief

A Phase 1 clinical trial evaluating BI 425809 and fluconazole for Healthy. Completed, enrolled 15 participants across 1 site.

Detailed Summary

The main objective of this trial is to investigate the effect of fluconazole, under steady state conditions on the pharmacokinetics of BI 425809 (Reference Treatment R: BI 425809 alone; Test Treatment T: BI 425809 given under steady state conditions of fluconazole).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesGermany
Collaborators--

Timeline

Phase 1CompletedFinished
20222023202420252026
First PostedOct 13, 2021
Enrollment StartOct 19, 2021
Primary CompletionJan 10, 2022
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 4.7 years ago

Interventions

BI 425809drug

Single oral dose of BI 425809 as film-coated tablet on Day 1 of period 1. Single oral dose of BI 425809 as film-coated tablet on Day 1 of period 2.

fluconazoledrug

Fluconazole orally as hard capsules once daily for 13 days (Day -4 up to Day 9) in period 2.