CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 250 enrolled
Drug / intervention
Ad26.RSV.preF-based vaccinebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05083585
NCT05083585Phase 3Completed

A Randomized, Double-blind Phase 3 Study to Compare the Immunogenicity of Clinical Trial Material of an Ad26.RSV.preF-based Vaccine for Phase 3 With Clinical Trial Material Representative of Phase 2b in Adults Aged 60 to 75 Years

Janssen Vaccines & Prevention B.V.·interventional·Posted Oct 19, 2021·Updated May 25, 2025

In Brief

A Phase 3 clinical trial evaluating Ad26.RSV.preF-based vaccine for Respiratory Syncytial Virus Prevention. Completed, enrolled 250 participants across 9 sites.

Detailed Summary

The purpose of this study is to demonstrate non-inferiority in terms of humoral immune responses induced by vaccination with one dose of the Phase 3 clinical trial material (CTM) compared with one dose of the Phase 2b CTM.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
20222023202420252026
First PostedOct 19, 2021
Enrollment StartOct 8, 2021
Primary CompletionMar 7, 2022
Study CompletionSep 22, 2022
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 4.7 years ago

Interventions

Ad26.RSV.preF-based vaccinebiological

Ad26.RSV.preF-based vaccine will be administered as a single intramuscular injection.