CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 800 enrolled
Drug / intervention
Investigational varicella vaccine low potency +7 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05084508
NCT05084508Phase 2Completed

A Phase II, Observer-blind, Randomized, Controlled Study to Evaluate the Immunogenicity and Safety of a Varicella Vaccine at Various Potencies Compared With Varivax, as a First Dose, Administered in Healthy Children in Their Second Year of Life

GlaxoSmithKline·interventional·Posted Oct 19, 2021·Updated Feb 28, 2025

In Brief

A Phase 2 clinical trial evaluating Investigational varicella vaccine low potency, Investigational varicella vaccine medium potency, and 6 other interventions for Chickenpox. Completed, enrolled 800 participants across 51 sites in 6 countries.

Detailed Summary

The purpose of this study is to assess immune response and safety of various potencies of an investigational chickenpox vaccine given to healthy children 12 to 15 months of age.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsChickenpox
CountriesEstonia, Poland, Puerto Rico, Taiwan, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedOct 19, 2021
Enrollment StartFeb 3, 2022
Primary CompletionFeb 9, 2024
Study CompletionJun 13, 2024
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 4.7 years ago

Interventions

Investigational varicella vaccine low potencybiological

1 dose of a low-potency investigational varicella vaccine administered subcutaneously.

Investigational varicella vaccine medium potencybiological

1 dose of a medium-potency investigational varicella vaccine administered subcutaneously.

Investigational varicella vaccine high potencybiological

1 dose of a high-potency investigational varicella vaccine administered subcutaneously.

Licensed varicella vaccine Lot 1biological

1 dose of a licensed varicella vaccine of Lot 1 administered subcutaneously.

Licensed varicella vaccine Lot 2biological

1 dose of a licensed varicella vaccine of Lot 2 administered subcutaneously.

Measles, mumps, and rubella vaccinebiological

1 dose of a measles, mumps, and rubella vaccine administered subcutaneously.

Hepatitis A vaccinebiological

1 dose of a hepatitis A vaccine administered intramuscularly.

13-valent pneumococcal conjugate vaccinebiological

1 dose of a 13-valent pneumococcal conjugate vaccine administered intramuscularly.