At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Examining the Effect of Salbutamol Use in Asthma and/or Exercise Induced Bronchoconstriction Whilst Exercising in Ozone Air Pollution
In Brief
A Phase 4 clinical trial evaluating Salbutamol, Placebo medication, and 3 other interventions for Asthma and/or Exercise Induced Bronchoconstriction and Ozone Air Pollution. Completed, enrolled 18 participants across 1 site.
Detailed Summary
Salbutamol use is increased in areas with high levels of ozone pollution and the potential consequences of this are not well known. The purpose of this study is to examine the effect of salbutamol on lung function and inflammation in people with asthma and/or EIB exercising in ozone air pollution. To examine this, we are planning a randomized cross over trial where people with asthma and/or EIB complete sub maximal exercise in four conditions on four separate days. The four condition are: ozone + salbutamol, filtered air + salbutamol, ozone + placebo medication, and filtered air + placebo medication.
Study Details
Timeline
Interventions
Inhaling 200ug of salbutamol
Inhaling placebo medication
Breathing 170ppb ozone
Breathing filtered air
Cycling at 60% of VO2max on a cycle ergometer