CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 984 enrolled / 984 target
Drug / intervention
Endoscopic injection sclerotherapy +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05089500
NCT05089500N/ACompletedHigh Momentum (17.6/mo)Completion was 3mo ago

Prospective Multicenter Clinical Study of Flexible Endoscopic Treatment for Grade I-III Internal Hemorrhoids

Renmin Hospital of Wuhan University·interventional·Posted Oct 22, 2021·Updated Jun 15, 2026

In Brief

A clinical study evaluating Endoscopic injection sclerotherapy and Endoscopic Band Ligation for Hemorrhoid and 5 related conditions. Completed, enrolled 984 participants across 2 sites.

Signals

Enrolling ahead of pace

Detailed Summary

This study is a prospective, multicentre, and randomized-controlled clinical study.The researchers wanted to explore the optimal treatment regimen for soft hemorrhoid within I-Ⅲ degrees by evaluating and comparing the effectiveness, safety and cost effect ratio of sclerosing injection and rubber lap ligation in patients with different internal hemorrhoid scores

Study Details

Timeline

N/ACompletedFinished
20222023202420252026
First PostedOct 22, 2021
Enrollment StartNov 1, 2021
Primary CompletionMar 29, 2026
TodayJul 2, 2026
Enrollment to primary: 4.4 yearsPosted 4.7 years ago

Arms & Interventions

Endoscopic injection sclerotherapyexperimental

Other: Endoscopic injection sclerotherapy
Endoscopic Band Ligationexperimental

Other: Endoscopic Band Ligation

Interventions

Endoscopic injection sclerotherapyother

Patients were randomized assigned to the EIS group, preparing disposable endoscopic injections and sclerosing which were routinely administered with 1% polycinol.The transparent cap was fixed at the front end of the endoscope in inverted or orthofield of view.The stiffening agent or foam stiffer added to Meilan was injected with a disposable injection needle at 4-6 points at the oral end near the dentate line. Each point contained 0.2-1ml, and stopped after the hemorrhoid nucleus changed color. If necessary, a transparent cap was pressed to stop the bleeding to distribute the stiffening agent evenly.

Endoscopic Band Ligationother

Patients were randomized assigned to the EBL group and were to be prepared before surgery.After the socket is mounted at the inner lens end, the socket is obviously tied at 1-2cm hemorrhoids at the mouth above the dentate line, usually 2-4 rings.With mucosal prolapse, pericyclic multiple dislocation ligation can be performed 2-3cm above the obvious prolapse.