At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 207 enrolled
Drug / intervention
Esketamine +1 moredrug
Likely dose
Esketamine 2 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Propofol Versus Ketamine for Rapid Sequence Intubation in Critically Ill Patients: A Randomized, Multicenter, Unblinded, Clinical Trial
In Brief
A Phase 2 clinical trial evaluating Esketamine and Propofol for Acute Respiratory Failure. Completed, enrolled 207 participants across 1 site.
Detailed Summary
Rapid-sequence intubation is routinely performed in critically ill patients. It is unclear whether different sedative agents may influence short-term outcomes after intubation, specially hemodynamic stability.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcute Respiratory Failure
CountriesBrazil
Collaborators--
Timeline
Phase 2CompletedFinished
20222023202420252026
Enrollment StartOct 2021
First PostedOct 2021
Primary CompletionOct 2023
Study CompletionDec 2023
TodayJul 2026
First PostedOct 25, 2021
Enrollment StartOct 23, 2021
Primary CompletionOct 31, 2023
Study CompletionDec 31, 2023
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 4.7 years ago
Interventions
Esketaminedrug
2 mg per kilogram of body weight
Propofoldrug
1.5 mg per kilogram of body weight