CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 142 enrolled
Drug / intervention
HMI-115 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05101317
NCT05101317Phase 2Completed

A Randomized, Multicenter, Double-Blind, Placebo-Controlled Phase 2 Study to Evaluate the Safety and Efficacy of HMI-115 in Women With Moderate to Severe Endometriosis-Associated Pain Over a 12-Week Treatment Period

Hope Medicine (Nanjing) Co., Ltd·interventional·Posted Nov 1, 2021·Updated Jan 21, 2026

In Brief

A Phase 2 clinical trial evaluating HMI-115 and Placebo for Endometriosis. Completed, enrolled 142 participants across 5 sites in 3 countries.

Detailed Summary

This study is designed to evaluate the safety and efficacy of HMI-115 compared to placebo over a 12 weeks period on subjects with moderate to severe endometriosis-associated pain.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsEndometriosis
CountriesChina, Poland, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedNov 1, 2021
Enrollment StartOct 11, 2021
Primary CompletionSep 26, 2024
Study CompletionMar 19, 2025
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 4.7 years ago

Interventions

HMI-115drug

HMI-115 is human monoclonal antibody

Placebodrug

Placebo