CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 755 enrolled
Drug / intervention
Ad26.RSV.PreF-based Vaccinebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05101486
NCT05101486Phase 3Completed

A Randomized, Double-blind Phase 3 Study to Assess the Immunogenicity and Safety of an Ad26.RSV.PreF-based Regimen at the End of Shelf-life in Adults Aged 60 to 75 Years

Janssen Vaccines & Prevention B.V.·interventional·Posted Nov 1, 2021·Updated May 25, 2025

In Brief

A Phase 3 clinical trial evaluating Ad26.RSV.PreF-based Vaccine for Respiratory Syncytial Virus Prevention. Completed, enrolled 755 participants across 13 sites.

Detailed Summary

The purpose of this study is to demonstrate non-inferiority in terms of humoral immune responses of Ad26.RSV.preF-based study vaccine lots representative of different aged vaccine in comparison to a non-aged Ad26.RSV.preF-based study vaccine lot.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
20222023202420252026
First PostedNov 1, 2021
Enrollment StartNov 1, 2021
Primary CompletionMar 28, 2022
Study CompletionSep 20, 2022
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 4.7 years ago

Interventions

Ad26.RSV.PreF-based Vaccinebiological

Ad26.RSV.PreF-based Vaccine will be administered as single IM injection.