At a glance
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Quantitative Electroencephalogram and Bispectral Index Brain Mapping During Propofol vs Sevoflurane General Anesthesia A Randomized Comparative Trial
In Brief
An observational study evaluating Propofol 1 % Injectable Suspension and Sevoflurane inhalant product for Neurophysiology. Completed, enrolled 40 participants.
Detailed Summary
General anesthesia interferes with the whole cerebral cortex at different levels. The goal was to investigate the impact of general anesthesia on different regions of the cerebral cortex by recording the brain's electrophysiological activity using QEEG and BIS during general anesthesia for 40 patients undergoing orthopedic surgeries under general anesthesia to see whether our hypothesis, that there is a topographically-dependent impact of general anesthesia on different regions of the cerebral cortex, is valid or not. The patients were randomly divided into 2 groups of 20 patients to compare the effect on the brain function monitoring (QEEG vs BIS) of the intravenous anesthesia (propofol) with the halogenated anesthesia (sevoflurane). And finally, we compared the two brain function monitoring techniques, BIS and QEEG.
Study Details
Timeline
Interventions
Induction and maintenance of general anesthesia using the intravenous anesthetic
Induction and maintenance of general anesthesia using the inhaled anesthetic sevoflurane