At a glance
ClinicalIndex Comparison RecordN/ACompleted· 44 enrolled
Drug / intervention
Nitroglycerin Topical Productdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Trial of a Topical Nitroglycerin Challenge to Detect Reversible Microcirculatory Dysfunction in Patients With Circulatory Shock.
In Brief
An observational study evaluating Nitroglycerin Topical Product for Circulatory Shock and Cardiovascular Shock. Completed, enrolled 44 participants across 1 site.
Detailed Summary
This is an open-label, single center, trial that will enroll up to 25 participants with circulatory shock after cardiac surgery. Participants will be administered a topical sublingual nitroglycerin solution and assessed for changes microcirculatory blood flow using incident dark field microscopy.
Study Details
Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsCirculatory Shock, Cardiovascular Shock
CountriesUnited States
Collaborators--
Timeline
N/ACompletedFinished
20222023202420252026
Enrollment StartSep 2021
First PostedNov 2021
Primary CompletionFeb 2022
Study CompletionMar 2022
TodayJul 2026
First PostedNov 1, 2021
Enrollment StartSep 1, 2021
Primary CompletionFeb 1, 2022
Study CompletionMar 1, 2022
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 4.7 years ago
Interventions
Nitroglycerin Topical Productdrug
Topical nitroglycerin solution