CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 318 enrolled
Drug / intervention
BI 1358894 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05103657
NCT05103657Phase 2Completed

A Phase II, 8-week-treatment, Multicenter, Randomized, Doubleblind, Placebo-controlled, Parallel Group Trial to Evaluate the Efficacy, Tolerability and Safety of Orally Administered BI 1358894 in Patients With Post-Traumatic Stress Disorder (PTSD)

Boehringer Ingelheim·interventional·Posted Nov 2, 2021·Updated Nov 7, 2024

In Brief

A Phase 2 clinical trial evaluating BI 1358894 and Placebo for Post-Traumatic Stress Disorder. Completed, enrolled 318 participants across 61 sites in 8 countries.

Detailed Summary

This study is open to people aged 18 to 65 who have post-traumatic stress disorder. The purpose of this study is to find out whether a medicine called BI 1358894 improves symptoms in people with post-traumatic stress disorder. Participants are put into 2 groups randomly, which means by chance. Participants take BI 1358894 or placebo as tablets every day for 2 months. Placebo tablets look like BI 1358894 tablets but do not contain any medicine. Participants are in the study for about 3 months. During this time, they visit the study site about 8 times and get about 4 phone calls from the trial staff. During the study, participants answer questions in interviews and complete questionnaires so the doctors can check whether their symptoms change. The doctors also regularly check participants' health and take note of any unwanted effects.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCroatia, Finland, Germany, Israel, Mexico, Poland, Sweden, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedNov 2, 2021
Enrollment StartDec 7, 2021
Primary CompletionOct 12, 2023
Study CompletionNov 20, 2023
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 4.7 years ago

Interventions

BI 1358894drug

BI 1358894

Placebodrug

Placebo