CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 19 enrolled
Drug / intervention
tDCS (Active) +2 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05111548
NCT05111548N/ACompleted

Neuromodulation Plus Cognitive Training to Improve Working Memory Among Individuals With Severe Mental Illness

University of Michigan·interventional·Posted Nov 8, 2021·Updated May 9, 2024

In Brief

A clinical study evaluating tDCS (Active), BrainHQ, and 1 other intervention for Schizophrenia and 2 related conditions. Completed, enrolled 19 participants across 1 site.

Detailed Summary

People with serious mental illness often experience difficulties with thinking skills like memory. These difficulties can make it harder to perform day-to-day activities. The purpose of this study is to test whether combining a type of non-invasive brain stimulation with computerized cognitive exercises is helpful in improving a specific type of memory skill in people who have mental health conditions. The study is a randomized clinical trial, meaning that participants will be randomly assigned to receive either 'active' or 'inactive' brain stimulation. All participants will complete computerized cognitive exercises, also known as cognitive training. Overall, participants will be in the study for 6-8 weeks. The study involves 10 visits to the clinic over 2-4 weeks for cognitive training and either active or inactive brain stimulation. Participants will also complete paper-and-pencil assessments at the beginning and end of treatment, and one month after treatment ends.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedNov 8, 2021
Enrollment StartSep 8, 2021
Primary CompletionApr 14, 2023
Study CompletionMay 12, 2023
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 4.6 years ago

Interventions

tDCS (Active)device

tDCS is a non-invasive procedure in which electrodes are attached to the scalp and send a small direct current to stimulate brain function. Participants in the experimental arm will receive a steady current delivery through the device.

BrainHQbehavioral

BrainHQ is a web-based, commercially available cognitive training program that includes exercises to enhance working memory

tDCS (Inactive)device

tDCS is a non-invasive procedure in which electrodes are attached to the scalp and send a small direct current to stimulate brain function. Participants in the sham arm will wear the device but will not receive a steady current delivery.