At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Twelve Week Safety and Clinical Efficacy of Experimental Mouth Rinses
In Brief
A Phase 4 clinical trial evaluating Colgate Cavity Protection Toothpaste, American Dental Association (ADA) Ref Toothbrush, and 5 other interventions for Gingivitis and Plaque. Completed, enrolled 300 participants across 1 site.
Detailed Summary
The purpose of this study is to evaluate the safety and efficacy of experimental mouth rinse formulations compared to a hydroalcohol control mouth rinse and a positive control mouth rinse for the reduction of gingivitis and plaque when used as an adjunct to tooth brushing during a twelve-week product usage period.
Study Details
Timeline
Interventions
Participants will use Colgate Cavity Protection Toothpaste for brushing teeth twice daily.
Participants will use soft bristled Toothbrush for brushing teeth twice daily.
Participants will use 20 mL of Prototype 1 Mouth Rinse for 30 seconds after brushing twice daily.
Participants will use 20 mL of Prototype 2 Mouth Rinse for 30 seconds after brushing twice daily.
Participants will use 20 mL of Prototype 3 Mouth Rinse for 30 seconds after brushing twice daily.
Participants will use 20 mL of Listerine Cool Mint Mouth Rinse for 30 seconds after brushing twice daily.
Participants will use 20 mL of Hydroalcohol Mouth Rinse for 30 seconds after brushing twice daily.