At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Twelve Week Safety/Clinical/Microbiological Efficacy of Experimental Mouthwashes
In Brief
A Phase 4 clinical trial evaluating Colgate (R) Cavity Protection Toothpaste, Colgate (R) Cello Toothbrush, and 5 other interventions for Gingivitis and Plaque. Completed, enrolled 274 participants across 1 site.
Detailed Summary
The purpose of this study is to evaluate the safety and efficacy of experimental mouthwash formulations compared to a hydroalcohol control mouthwash and a positive control mouthwash for the reduction of gingivitis and plaque when used as an adjunct to tooth brushing during a twelve-week product usage period.
Study Details
Timeline
Interventions
Participants will use Colgate (R) Cavity Protection Toothpaste for brushing teeth twice daily.
Participants will use Colgate (R) Cello Toothbrush for brushing teeth twice daily.
Participants will use 20 mL of Prototype 1 Mouthwash for 30 seconds after brushing twice daily.
Participants will use 20 mL of Prototype 2 Mouthwash for 30 seconds after brushing twice daily.
Participants will use 20 mL of Prototype 3 Mouthwash for 30 seconds after brushing twice daily.
Participants will use 20 mL of Listerine (R) Cool Mint (R) Antiseptic Mouthwash for 30 seconds after brushing twice daily.
Participants will use 20 mL of 5% Hydroalcohol Mouthwash for 30 seconds after brushing twice daily.